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Bruk av zopiklon kan føre til utvikling av misbruk og/eller fysisk og psykisk avhengighet. Faren for avhengighet øker med dose og varighet av behandlingen og er større når zopiklon brukes lenger enn four uker.Therapy of rats with zopiclone increases hepatic thyroid hormone metabolism of T4, causing raises in TSH and T3 amounts, and decrea
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